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HMGBIOTECH DISULFIDE HMGB1說明書

更新時間:2024-03-15      點擊次數:388

HMGBIOTECH   高遷移率蛋白、質粒、抗體


hmgbiotech HM-120

HMGB 1是細胞核的一個組成部分,在基因組的組織和表達中具有多種功能。HMG生物技術SRL為活躍在這一領域的其他研究人員和公司提供試劑、服務和想法。它還有助于實驗室開發(fā)分析和試劑。


hmgbiotech  DISULFIDE HMGB1說明書


hmgbiotech HM-120


HMGB1是一種核蛋白,其由壞死細胞被動釋放,由凋亡細胞保留,并由炎癥細胞主動分泌(Dumitriu等人,HMGB1:從內部引導免疫。Trends Immunol 2005,26:381-7)。HMGB1對生命至關重要:HMGB1基因敲除小鼠出生后不久死亡。

HMGB1作為運動細胞的化學引誘劑和細胞因子的誘導劑的兩種不同活性被歸因于不同的生物化學形式。還原的HMGB1(具有化學引誘活性的形式)被還原;二硫化物HMGB1包含C23和C45之間的二硫鍵(完整注釋:HMGB1C23-C45C106h–Antoine J.等人(2014)。Mol-Med)。

二硫化物HMGB1可誘導單核細胞和其他炎癥細胞產生細胞因子和趨化因子(Venereau等人,2012)。

在結構上,二硫化物HMGB1在半胱氨酸殘基23和45與還原的半胱氨酸殘基106之間具有二硫鍵。測試二硫化物HMGB1刺激細胞因子的能力




HMGBiotech公司熱銷產品

產品名稱

貨號

100 ug Fully reduced HMGB1, LPS free

HM-115

50 ug Fully reduced HMGB1, LPS free

HM-116

100 ug Disulfide HMGB1, LPS free

HM-121

100 ug BoxA from HMGB1, LPS-free and tested in migration assay

HM-012

50 ug Disulfide HMGB1, LPS free

HM-122

500 ug BoxA from HMGB1, LPS-free and tested in migration assay

HM-013

1 mg HMGB1 for biochemistry

HM-100

2.5 mg BoxA from HMGB1, LPS-free and tested in migration assay

HM-014

250 ug HMGB1 biochemistry

HM-101

25 ug BoxA from HMGB1, LPS-free and tested in migration assay

HM-011

15 ug BoxB from HMGB1, LPS-free and tested in migration assay

HM-053

15 ug Fully reduced HMGB1, LPS free

HM-117

10 ug Disulfide HMGB1, LPS free

HM-123

15 ug Non-oxidizable HMGB1, LPS free

HM-133

250 ug Stromal Cell-Derived Factor 1α (SDF-1α, CXCL12) tested in migration

HM-170

100 ug Stromal Cell-Derived Factor 1α (SDF-1α, CXCL12) tested in migration

HM-171

50 ug Stromal Cell-Derived Factor 1α (SDF-1α, CXCL12) tested in migration

HM-172

15 ug Stromal Cell-Derived Factor 1α (SDF-1α, CXCL12) tested in migration

HM-173

50 ug HMGB1 15N labelled for Mass Spectrometry

HM-180

5 ug HMGB1 15N labelled for Mass Spectrometry

HM-181

2.5 mg BoxA 2D from HMGB1, LPS-free and tested in migration assay

HM-190

500 ug BoxA 2D from HMGB1, LPS-free and tested in migration assay

HM-191

100 ug BoxA 2D from HMGB1, LPS-free and tested in migration assay

HM-192

25 ug BoxA 2D from HMGB1, LPS-free and tested in migration assay

HM-193

Control cell lysates from Hmgb1 +/+

HM-001

Control cell lysates from Hmgb1 -/-

HM-002

1 mg BoxB from HMGB1, LPS-free and tested in migration assay

HM-050

250 ug BoxB from HMGB1, LPS-free and tested in migration assay

HM-051

100 ug BoxB from HMGB1, LPS-free and tested in migration assay

HM-052

500 ug Fully reduced HMGB1, LPS free

HM-114

250 ug Disulfide HMGB1, LPS free

HM-120

500 ug Non-oxidizable HMGB1, LPS free

HM-130

100 ug Non-oxidizable HMGB1, LPS free

HM-131

50 ug Non-oxidizable HMGB1, LPS free

HM-132

500 ug HMGB2, LPS-free and tested in migration assay

HM-151

100 ug HMGB2, LPS-free and tested in migration assay

HM-152

50 ug HMGB2, LPS-free and tested in migration assay

HM-153

Embryonic fibroblasts immortalized with large T antigen. One vial of -/- cells and one vial of +/+ cells

HM-201

Embryonic fibroblasts immortalized with the 3T3 method. One vial of -/- cells and one vial of +/+ cells

HM-221

Embryonic fibroblasts, Hmgb1-/- and HMGB2-low, immortalized with the 3T3 method. One vial of cells, and

HM-223

HMGB1 Isoforms Kit - Test size

HM-030

Embryonic fibroblasts immortalized with the 3T3 method. One vial of Hmgb2-/- cells and one vial of +/+ cells

HM-251

HMGB1 Isoforms Kit - Regular size

HM-031

20 ug p-mHMG1

HM-300

50 ug Terminally oxidized HMGB1, LPS free

HM-062

20 ug p-mHMG1tag

HM-301

100 ug Terminally oxidized HMGB1, LPS free

HM-061

20 ug pEGFP-HMGB1

HM-302

250 ug Terminally oxidized HMGB1, LPS free

HM-060

20 ug pcDNA/FL-RAGE plasmid

HM-310



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